Pain Syndrome	Associated Signs and Symptoms	Affected Nerves
Tumor infiltration of a peripheral nerve	Constant burning pain with dysesthesia in an area of sensory loss.	Peripheral nerves
	Pain is radicular and often unilateral.
Postradical neck dissection	Tight burning sensation in the area of sensory loss.	Lower cranial nerves
	Dysesthesias and shocklike pain may be present.
	Musculoskeletal pain may be caused by a drooped-shoulder syndrome.	Cervical plexus
Postmastectomy pain	Tight, constricting, burning pain in the posterior arm, axilla, and anterior chest wall.	Intercostobrachial
	Pain exacerbated by arm movement, possibly caused by musculoskeletal dysfunction or edema.
Postthoracotomy pain	Aching sensation in the distribution of the incision with sensory loss with or without autonomic changes.	Intercostal
	Often exquisite point tenderness at the most medial and apical points of the scar with a specific trigger point in the muscle.
Postnephrectomy pain	Numbness, fullness, or heaviness in the flank, anterior abdomen, and groin.	Superficial cutaneous nerves
	Dysesthesias are common.
Postamputation pain	Persistent, severe phantom limb pain in a minority of patients.	Peripheral nerves and their central projections
	Stump pain generally resolves with wound healing, although pain associated with scar sensitivity may emerge after months or years.
Chemotherapy-induced peripheral neuropathy	Painful paresthesias and dysesthesias.	Peripheral nerves (e.g., polyneuropathy)
	Hyporeflexia.
	Less frequently: motor and sensory loss; rarely: autonomic dysfunction.
	Commonly associated with the vinca alkaloids (e.g., vincristine, vinblastine), cisplatin, and paclitaxel.
Peripheral nerve tumors	Radiation therapy may promote malignant fibrosarcoma.	Peripheral nerves
	Painful, enlarging mass in a previously irradiated area.
	Patients with neurofibromatosis more susceptible.
Cranial neuropathies	Severe head pain with cranial nerve dysfunction.	Cranial nerves V, VII, IX, X, XI, XII are most common.
	Leptomeningeal disease.
	Base of skull metastasis.
Acute and postherpetic neuralgia	Painful paresthesia and dysesthesia.	Thoracic and cranial nerve V are most common.
	Constant burning and aching pain.
	Shocklike paroxysmal pain.
	Immunosuppression from disease or treatment is a risk factor; postherpetic neuropathy incidence increases with age.