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Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®)
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Table 3. BFM Relapse Risk Group Assignment for T-cell ALL*

  Extramedullary Relapse  Combined Bone Marrow and Extramedullary Relapse  Marrow Relapse 
*Adapted from Roy et al. [13] and Borgmann et al.[21]
Very Early Relapse (<18 months from diagnosis) Intermediate High High
Early Relapse (>18 months from diagnosis and <6 months from completion of therapy) Intermediate High High
Late Relapse (>6 months from completion of therapy) Standard High High

References

  1. Roy A, Cargill A, Love S, et al.: Outcome after first relapse in childhood acute lymphoblastic leukaemia - lessons from the United Kingdom R2 trial. Br J Haematol 130 (1): 67-75, 2005.  [PUBMED Abstract]

  2. Borgmann A, von Stackelberg A, Hartmann R, et al.: Unrelated donor stem cell transplantation compared with chemotherapy for children with acute lymphoblastic leukemia in a second remission: a matched-pair analysis. Blood 101 (10): 3835-9, 2003.  [PUBMED Abstract]


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