The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

General Information

Revised text to state that approximately 80% of childhood Hodgkin lymphoma cases with mixed-cellularity histology seen in developing countries are EBV positive (added Chabay et al. as reference 14).

Staging and Diagnostic Evaluation

Added Simpson et al. as reference 4.

Added Gallamini et al. as reference 13.

Treatment Approach for Children and Adolescents with Hodgkin Lymphoma

Added text to state that patients with nodular lymphocyte-predominant Hodgkin lymphoma are treated on risk-appropriate, classical Hodgkin lymphoma protocols.

Treatment of Primary Progressive/Recurrent Hodgkin Lymphoma in Children and Adolescents

Added Akhtar et al. as reference 16.

Added Schulz et al. as reference 24.

Late Effects from Childhood/Adolescent Hodgkin Lymphoma Therapy

Added Niinimäki et al. as reference 1.

Added text to state that the risk of secondary malignant neoplasm increases with radiation dose (cited Constine et al. as reference 62 and level of evidence 3iii).

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