The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Treatment Option Overview

Added text about preliminary results from a phase III randomized control trial of 5-azacitidine versus other regimens (cited Fenaux et al. as reference 23 and level of evidence 1iiA).

Added Soriano et al. as reference 33.

De Novo and Secondary Myelodysplastic Syndrome

This section was extensively revised.

Previously Treated Myelodysplastic Syndrome

Added text to the treatment options under clinical evaluation to include combination regimens and thrombopoietic agents.

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