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Table 1. Standard Chemotherapy Regimens for Wilms Tumor
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Regimen Name
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Regimen Description
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| Regimen EE-4A [1] |
vincristine, dactinomycin x 18 weeks post-nephrectomy |
| Regimen DD-4A [1] |
vincristine, dactinomycin, doxorubicin x 24 weeks post nephrectomy |
| Regimen I [2] |
vincristine, doxorubicin, cyclophosphamide, etoposide x 24 weeks |
References
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Green DM, Breslow NE, Beckwith JB, et al.: Comparison between single-dose and divided-dose administration of dactinomycin and doxorubicin for patients with Wilms' tumor: a report from the National Wilms' Tumor Study Group. J Clin Oncol 16 (1): 237-45, 1998.
[PUBMED Abstract]
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Dome JS, Cotton CA, Perlman EJ, et al.: Treatment of anaplastic histology Wilms' tumor: results from the fifth National Wilms' Tumor Study. J Clin Oncol 24 (15): 2352-8, 2006.
[PUBMED Abstract]
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